Grace Porter is reeling from grief after her partner of seven years unexpectedly leaves. Amidst her heartache, the thirty-year-old library tech is tasked with reading newly discovered letters that Amelia Earhart wrote to her lover, Gene Vidal. She becomes captivated by the famous pilot who disappeared in 1937. Letter by letter, Grace understands more about Amelia while piecing her own life back together.

When Grace discovers she is pregnant, her life becomes more intertwined with the aviation hero and she begins to write her own letters to Amelia. While navigating her third trimester—amidst new conspiracy theories about Amelia's mysterious disappearance, the search for her remains, and the impending publication of her private letters—Grace goes on a pilgrimage of her own.

Underscoring the power of reading and writing letters for self-discovery, Letters to Amelia is, above all, a story of the essential need for connection—and our universal ability to find hope in the face of fear.